Accutane causes insulin resistance and may lead to diabetes for some individuals.
More complications with Accutane. Researchers at Helsinki University in Finland discovered that Accutane causes insulin resistance and worsening of blood sugar controls.
CONCLUSION: Treatment of acne with 13-cis-retinoic acid reduces insulin sensitivity and induces alterations in lipid metabolism resembling those of the insulin resistance syndrome.
Here’s another study.
According to the studies Accutane induced insulin resistance is temporary and disappears after the treatment.
However this is not always the case and some unlucky people go on to develop a full-blown diabetes.
Here are two alarming stories from Accutane and diabetes forum.
I started taking Accutane at age 13. The blood tests were going good. You are supposed to get a blood test after every month. And You are on it for 8 months. And you get a last bllod test after you are off it after four weeks to make sure it is out of your system. So there are 9 blood tests total. On my 6th blood test my blood sugar was 132. It was a little high. Then on my 7th blood test it was 287. They wanted me to see a doctor right away so my mom pulled me out of school and brought me to a doctor, where I got another blood test. And my blood sugar was 430. So my doctor told me I had type 1 diabetes. No one in my family had diabetes that I know of except for my great uncle, who was diagnosed with diabetes at age 77. So im pretty sure the drug triggered it.
My daughter started Accutane 34 days ago with perfect sugar levels. After her first month on Accutane, we went to the Dtr and were told everything was fine but that she had higher than expected cholestrol, everything else was normal per the lab. Not to worry about the cholestrol. My daughter noted to the dtr that she was thirsty, but since the labs normals, dtr told us everything ok, increased the Accutane, gave her a cholestrol medication. Understand that this was one of the top dermatologist in our state who assured us all was fine.
She started the increased dose three days later. Two days from start of new dosage she is weak and is very thirsty. Visit to the ER, she had a sugar level of over 600 and diagnosed her with Type 1 diabetes.. they are telling us there is no connection and that it is genetic. In less than a week she went from normal to life threatening with no other changes in her life but the drug… she is not overweight and is 15.
Coincidence? Possibly and we can’t establish a firm link between Accutane and diabetes. However Google search of ‘Accutane diabetes’ reveals an alarming number of such coincidences. Diabetes is also mentioned as a risk factor for Accutane in drug manuals.
Though these incidences are rare type 1 diabetes (the one that most people got) is a permanent complication. Type 1 diabetes is diagnosed when the pancreas stops producing insulin. After that you have to inject insulin after every meal. Type 1 diabetes is a permanent condition with no known cure.
Just one more reason to avoid Accutane and stick to natural methods – especially since they are cheaper and often even work faster than Accutane.
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